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Dormosedan Gel is a sedative gel that is administered orally and is used to reduce anxiety and facilitate handling during clinical examinations and procedures in horses and dogs. It is designed to be absorbed through the thin membranes in the mouth and is not meant to be swallowed, as it will be degraded by digestive enzymes and have no effect. While the gel is typically administered under the tongue, some people have found success administering it on treats or in the inside of the lip. Does this oral gel, designed to be absorbed through the mouth, reduce gut sounds?
| Characteristics | Values |
|---|---|
| Purpose | To reduce anxiety and facilitate handling during clinical examinations and procedures in adult horses |
| Administration | Under the tongue (sublingually) or between the lip and gum |
| Effectiveness | Reduced when mixed with food or given in something other than its intended form |
| Side Effects | Increased sweating, ataxia, salivation, decreased body temperature, decreased respiratory rate, decreased gastric motility, decreased heart rate, increased urination, increased nasal discharge |
| Safety | Safe for dogs and horses |
| Availability | Veterinarian-prescribed or purchased from MWI Veterinary Supply |
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What You'll Learn
How to administer Dormosedan Gel
Dormosedan Gel is a sedative used to reduce anxiety and facilitate handling during clinical examinations, non-painful procedures, and routine husbandry procedures in adult horses. It is important to note that this medication is only intended for use in horses and should be administered as directed by a veterinarian.
- Wear Impermeable Gloves: Before handling the gel or syringe, put on impermeable gloves to protect your skin from direct exposure to the medication, as it can be absorbed through the skin and cause irritation.
- Prepare the Dose: Determine the appropriate dose based on the weight of the horse, following the dosing instructions provided by your veterinarian. The medication is typically delivered in 0.25ml increments using a single-dose syringe.
- Administer Under the Tongue: Dormosedan Gel is designed to be administered sublingually, which means it should be applied under the horse's tongue. Place the syringe under the tongue and slowly dispense the medication. Alternatively, you can use your gloved finger to smear the gel under the tongue, ensuring it comes into contact with the thin membranes in the mouth for absorption.
- Avoid Food and Water: Withhold food and water from the horse until the sedative effects have worn off. This is important because the horse's mouth should be empty during administration to ensure optimal absorption, and eating or drinking afterward may interfere with the intended effects of the medication.
- Provide a Comfortable Environment: Keep the horse in a quiet and comfortable environment before, during, and after treatment. This helps minimize stress and ensures the horse remains calm and relaxed, allowing the medication to take effect effectively.
- Discard Used Syringe: The dosing syringe is intended for one-time use. Properly discard the syringe after administration to prevent reuse and potential contamination.
- Monitor for Side Effects: Dormosedan Gel may cause side effects such as increased sweating, ataxia (unstable or uncoordinated movement), salivation, decreased body temperature, decreased respiratory rate, decreased gastric motility, decreased heart rate, increased urination, and increased nasal discharge. Monitor the horse closely and consult your veterinarian if any adverse reactions occur.
Remember, it is crucial to follow the specific instructions provided by your veterinarian, as they may have additional recommendations or precautions based on your horse's individual needs and health status.
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Effectiveness of Dormosedan Gel
Dormosedan Gel is a sedative designed to reduce anxiety and facilitate handling during clinical examinations, non-painful procedures, and routine husbandry procedures in adult horses. It is also used to facilitate handling in dogs. The gel contains 7.6 mg of detomidine hydrochloride per ml, an alpha-2 adrenergic agonist that produces reliable and reversible sedative effects.
The gel is administered sublingually, meaning it is applied under the tongue, and should not be swallowed. It is important to wear gloves when handling and administering the gel. The dosage is 0.018 mg per lb of body weight, with each 3 ml oral syringe formulated for horses weighing between 1,210 and 1,320 lbs. The gel provides fast-acting, precise, and effective sedation, making it a popular choice among veterinarians and horse owners.
However, it is important to note that Dormosedan Gel should only be administered as directed by a veterinarian. Mixing with other drugs or administering it with food can reduce its effectiveness. Additionally, it is more potent than similar drugs like Sedalin, so caution must be exercised with dosage.
In a study on the use of oral transmucosal (OTM) detomidine hydrochloride gel in dogs, six healthy laboratory dogs were given 0.35 mg/m2 via the OTM route. Five out of six dogs achieved adequate sedation, with four of the six dogs achieving sedation within 45 minutes and a duration of approximately 30 minutes. This demonstrates the effectiveness of Dormosedan Gel in facilitating handling in dogs by reducing anxiety and improving tractability.
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Dormosedan Gel for dogs
Dormosedan Gel is a sedative that is used to reduce anxiety and facilitate handling during clinical examinations, non-painful clinical procedures, and routine procedures in adult horses. It is an oral transmucosal (OTM) sedative that is placed under the tongue (sublingually) and absorbed through the mucus membranes. It is important to note that Dormosedan Gel is designed for horses and not for human use.
When it comes to its use in dogs, Dormosedan Gel has been studied for its potential to facilitate handling in dogs during veterinary visits. It is a synthetic alpha2-adrenoreceptor agonist with sedative properties, commercially available as an OTM formulation approved for sedation and restraint in horses. The use of Dormosedan Gel in dogs aims to simplify the experience for both the dog and the veterinary staff by reducing anxiety and aggression triggered by fear. This proactive approach helps prevent the escalation of fear and the negative associations dogs develop with veterinary clinics.
To administer Dormosedan Gel to dogs, it is recommended to use a carefully measured dose based on the dog's surface area converted from its weight in kilograms. The gel is placed between the lower lip and gum, near the back of the dog's lower dental arcade, using a syringe. It is important to ensure that the dog does not swallow the gel, as it will be degraded by digestive enzymes and rendered ineffective. The dog's mouth should be held closed and in an upward position for about two minutes to allow for proper absorption.
It is important to note that Dormosedan Gel should be handled with caution. Accidental exposure can cause adverse reactions, including sedation, hypotension, and bradycardia. It is recommended to wear impermeable gloves during administration and to avoid skin and mucosal contact with the product. Additionally, individuals with cardiovascular disease should take extra precautions to avoid exposure.
In conclusion, Dormosedan Gel has been explored as a potential solution for anxious and aggressive dogs during veterinary visits. By administering this OTM sedative, dog owners and veterinary staff can create a calmer and safer environment for everyone involved, improving the overall veterinary experience for fearful dogs.
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Dormosedan Gel for horses
Dormosedan Gel is a sedative used to reduce anxiety and facilitate handling in adult horses during clinical examinations, non-painful clinical procedures, and routine husbandry procedures. It is designed to be administered sublingually (under the tongue) and should not be swallowed. The active ingredient in Dormosedan Gel is detomidine, which provides precise and effective sedation. The medication is delivered in 0.25ml increments using a dosing syringe, with the dosage tailored to the weight of the horse. It is important to wear impermeable gloves when handling and administering the gel, as it can be absorbed through the skin and cause irritation. Additionally, food and water should be withheld until the sedative effects have worn off.
Dormosedan Gel is a convenient solution for occasional use when horses need a mild sedative before stressful situations or minor procedures. It is fast-acting and provides reliable sedation, making it a popular choice among equine professionals. The gel is also palatable and easier to administer compared to other sedatives. However, it is important to note that Dormosedan Gel should not be used in horses with pre-existing atrioventricular or sinoatrial blocks, cardiovascular disease, respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold, fatigue, or high altitude.
When administering Dormosedan Gel, it is crucial to follow the instructions provided by your veterinarian. The gel should be placed under the horse's tongue, and the horse should be kept in a quiet and comfortable environment before, during, and after treatment. Some horses may try to spit out the gel, so it can be helpful to administer it with treats or sandwiches to ensure the full dose is consumed. It is important to be careful with the dosage as Dormosedan Gel is more potent than other sedatives like Sedalin.
While Dormosedan Gel is a safe and effective sedative for horses, it is a prescription medication that should only be used under the guidance of a veterinarian. Side effects may include increased sweating, ataxia (unstable/uncoordinated movement), salivation, decreased body temperature, decreased respiratory rate, decreased gastric motility, decreased heart rate, increased urination, and increased nasal discharge. If any adverse effects are observed, it is important to consult with a veterinarian immediately.
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Side effects of Dormosedan Gel
Dormosedan Gel is a prescription medication used to mildly sedate horses. It is important to note that this medication is not intended for human use and should be kept out of the reach of children. When handling and administering Dormosedan Gel, it is recommended to wear impermeable disposable gloves to avoid direct exposure to the skin, mucous membranes, or eyes.
- Prolonged Sedation: The sedative effects of Dormosedan Gel can last for approximately 90 to 180 minutes. It is important to allow adequate time, usually a minimum of 40 minutes, between administering the gel and starting any procedures.
- Increased Sweating: Horses may experience increased sweating as a side effect of the medication.
- Ataxia: Ataxia refers to unstable or uncoordinated movements, which may be observed in horses administered Dormosedan Gel.
- Excessive Salivation: The medication can cause an increase in salivation, leading to drooling.
- Decreased Body Temperature: A reduction in body temperature may occur as a side effect.
- Decreased Respiratory Rate: Dormosedan Gel can lead to a decrease in the horse's respiratory rate.
- Decreased Gastric Motility: This side effect refers to a reduction in the normal contractions of the stomach, which may impact digestion.
- Bradycardia: Horses may experience a decreased heart rate, which is a known side effect of the medication.
- Increased Urination: Dormosedan Gel can cause an increase in urination in treated horses.
- Nasal Discharge: There may be an increase in nasal discharge, which can be observed around the horse's nostrils.
- Contraindications: Dormosedan Gel should not be used in horses with certain medical conditions, including abnormal heart rhythms, heart failure, cerebrovascular disease, respiratory disease, chronic kidney failure, shock, severe debilitation, or known hypersensitivity to the medication. It is also not recommended for horses that are already sedated, under anesthesia, or experiencing stress due to fatigue, high altitude, or extreme temperatures.
- Age and Breed Restrictions: The safety of Dormosedan Gel has not been evaluated in horses younger than one year of age, ponies, miniature horses, or breeding, pregnant, or lactating horses.
It is always advisable to consult with a veterinarian before administering Dormosedan Gel to ensure it is used appropriately and safely.
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Frequently asked questions
Dormosedan Gel is a sedative used to reduce anxiety and facilitate handling during clinical examinations, non-painful procedures, and routine husbandry procedures in adult horses. It is also used in dogs to reduce stress during minor procedures and alleviate acute anxiety and fear associated with noise.
Dormosedan Gel is designed to be absorbed through thin membranes in the mouth, specifically under the tongue, and not through the gut. It is not meant to be swallowed as it will be degraded by digestive enzymes and will not be effective.
The onset of sedation usually takes about 40 minutes, and the sedative effect lasts about 90 to 180 minutes. It is recommended to keep the horse or dog in a quiet area during this time and withhold food and water until the sedative has worn off.
Yes, side effects may include increased sweating, ataxia (unstable/uncoordinated movement), salivation, decreased body temperature, decreased respiratory rate, decreased gastric motility, decreased heart rate, increased urination, and increased nasal discharge. It is important to carefully follow the instructions provided by your veterinarian.
